GLUD1

gene product
GDH, GLUD
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
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GeneTex
2 antibodies
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antibodies-online
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Arigo
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1 antibody
Cell Signaling Technology, Inc
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1 antibody
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2 antibodies
ProSci
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1 antibody
Boster Biological Technology
1 antibody
MyBioSource
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RayBiotech, Inc.
3 antibodies
RabMAbs
2 antibodies
Leading Biology
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GenWay
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United States Biological
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Abgent
3 antibodies
EMD Millipore
1 antibody
Sigma-Aldrich
2 antibodies