PDE6A

gene product
PDEA, RP43
This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008]
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Proteintech Group
1 antibody
Novus Biologicals
4 antibodies
Atlas Antibodies
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
GeneTex
2 antibodies
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antibodies-online
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Invitrogen Antibodies
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Affinity Biosciences
1 antibody
Biorbyt
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Acris Antibodies GmbH
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OriGene
3 antibodies
Aviva Systems Biology
2 antibodies
Abnova Corporation
1 antibody
MyBioSource
3 antibodies
ProSci
2 antibodies
Boster Biological Technology
1 antibody
St John's Laboratory
1 antibody
Abbexa
4 antibodies
Sigma-Aldrich
3 antibodies
United States Biological
15 antibodies
Abgent
2 antibodies
Creative Diagnostics
1 antibody
Exalpha Biologicals, Inc.
1 antibody
GenWay
1 antibody
Leading Biology
1 antibody
RayBiotech, Inc.
1 antibody