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Protein structure
APLP1
Amyloid beta precursor like protein 1APLP
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  12305-2-AP |
4 references | Polyclonal |
WB
EL
IP
IHC
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| LSBio | LS-C834130 |
Polyclonal |
WB
IHC
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| Novus Biologicals | NBP2-67160 |
Monoclonal |
WB
ICC
IHC
FC
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| Invitrogen Antibodies | 12305-2-AP |
Polyclonal |
WB
IP
IHC
OA
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| R&D Systems | AF3129 |
1 references | Polyclonal |
WB
IP
IHC
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