CYP3A7

This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3AP1 pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Apr 2014]

Description

cytochrome P450 family 3 subfamily A member 7

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

7:q22.1 (99705037 - 99735196)

Ensembl ID

ENSG00000160870  (ver. 84.38)

Orthologs

-

UniProt

P24462

neXtProt

NX_P24462

Human splice variants