KPNA6

gene product
FLJ11249, IPOA7, KPNA7, MGC17918
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
175 antibodies from 31 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
3 antibodies
antibodies-online
64 antibodies
Abnova Corporation
5 antibodies
OriGene
5 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
5 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
Acris Antibodies GmbH
4 antibodies
LifeSpan BioSciences, Inc.
14 antibodies
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Arigo
3 antibodies
Biorbyt
13 antibodies
GeneTex
3 antibodies
Aviva Systems Biology
3 antibodies
Rockland Immunochemicals, Inc.
1 antibody
ProSci
2 antibodies
St John's Laboratory
2 antibodies
Abgent
2 antibodies
Bioworld Technology, Inc
1 antibody
MyBioSource
4 antibodies
Creative Diagnostics
4 antibodies
Bioss
3 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
13 antibodies
Abbexa
5 antibodies
Leading Biology
3 antibodies
Sigma-Aldrich
3 antibodies
EMD Millipore
1 antibody