Tissue expression
Cell line expression
DLD
gene productDLDH, E3, GCSL, LAD, OGDC-E3
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Featured antibodies
![]() |
![]() |
0 references | Polyclonal |
WB
ICC IHC
|
![]() |
![]() |
0 references | Polyclonal |
WB
ICC IHC
|