ABCC2

gene product
CMOAT, cMRP, DJS, MRP2
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
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299 antibodies from 32 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
99 antibodies
Novus Biologicals
6 antibodies
Proteintech Group
1 antibody
GeneTex
5 antibodies
Biorbyt
36 antibodies
NovoPro Bioscience Inc.
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Boster Biological Technology
1 antibody
LifeSpan BioSciences, Inc.
44 antibodies
OriGene
7 antibodies
Abnova Corporation
7 antibodies
Atlas Antibodies
1 antibody
Enzo Life Sciences
2 antibodies
Invitrogen Antibodies
8 antibodies
Abgent
3 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
2 antibodies
Creative Diagnostics
4 antibodies
GenWay
6 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
Acris Antibodies GmbH
4 antibodies
St John's Laboratory
2 antibodies
Abbiotec
1 antibody
Bethyl Laboratories
1 antibody
RabMAbs
1 antibody
United States Biological
26 antibodies
MyBioSource
4 antibodies
EMD Millipore
2 antibodies
Sigma-Aldrich
4 antibodies
BioLegend (formerly Covance Antibody Products)
2 antibodies