WNT16

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008]

Description

Wnt family member 16

Tissue specificity

Tissue enhanced (cervix, skin)

Predicted location

Intracellular, Secreted to extracellular matrix

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted secreted proteins

Chromosome

7 (121325367 - 121341104)

Ensembl ID

ENSG00000002745  (ver. 103.38)

Orthologs

Mouse Wnt16: ENSMUSG00000029671

UniProt

Q9UBV4

neXtProt

NX_Q9UBV4

Human splice variants
Mouse splice variants

Protein structure