PICALM

gene product
CALM, CLTH
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
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Antibodies

 

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200 antibodies from 32 providers.

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Antibody
Invitrogen Antibodies
6 antibodies
Novus Biologicals
6 antibodies
GeneTex
3 antibodies
Atlas Antibodies
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
antibodies-online
88 antibodies
OriGene
2 antibodies
LifeSpan BioSciences, Inc.
24 antibodies
Biorbyt
14 antibodies
Aviva Systems Biology
2 antibodies
Rockland Immunochemicals, Inc.
1 antibody
Acris Antibodies GmbH
3 antibodies
Abgent
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bethyl Laboratories
1 antibody
ProSci
1 antibody
Proteintech Group
1 antibody
Abnova Corporation
3 antibodies
Creative Diagnostics
4 antibodies
Leading Biology
5 antibodies
MyBioSource
3 antibodies
St John's Laboratory
2 antibodies
Abiocode, Inc.
1 antibody
Creative Biolabs
1 antibody
RabMAbs
1 antibody
RayBiotech, Inc.
1 antibody
eBioscience, An Affymetrix Company
8 antibodies
Sigma-Aldrich
2 antibodies
Abbexa
5 antibodies
Abbiotec
1 antibody
EMD Millipore
1 antibody
United States Biological
1 antibody