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Cell line expression
Protein structure
RNF7
Ring finger protein 7CKBBP1, ROC2, SAG
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  11905-1-AP |
3 references | Polyclonal |
WB
EL
ICC
IP
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| LSBio | LS-C392690 |
Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | 11905-1-AP |
Polyclonal |
WB
ICC
IP
OA
|
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| Atlas Antibodies | HPA036995 |
Polyclonal |
WB
ICC
IHC
|
||
| Novus Biologicals | NBP1-46159 |
1 references | Polyclonal |
WB
EL
IHC
|
|
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