Tissue expression
Cell line expression
Protein structure
EIF2B3
Eukaryotic translation initiation factor 2B subunit gammaEIF-2B, EIF2Bgamma
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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| Invitrogen Antibodies | Monoclonal |
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| Proteintech Group | 2 references | Polyclonal |
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| LSBio | Monoclonal |
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| GeneTex | Monoclonal |
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| Atlas Antibodies | Polyclonal |
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