POLH

gene product
RAD30A, XP-V
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
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Eligible for validation within AVI
182 antibodies from 28 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Biorbyt
10 antibodies
antibodies-online
69 antibodies
GeneTex
2 antibodies
OriGene
3 antibodies
Invitrogen Antibodies
4 antibodies
LifeSpan BioSciences, Inc.
14 antibodies
Bioworld Technology, Inc
1 antibody
Affinity Biosciences
1 antibody
Novus Biologicals
8 antibodies
Abnova Corporation
4 antibodies
Atlas Antibodies
2 antibodies
Bethyl Laboratories
2 antibodies
St John's Laboratory
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abgent
1 antibody
NSJ Bioreagents
1 antibody
R&D Systems
1 antibody
United States Biological
24 antibodies
Creative Biolabs
3 antibodies
MyBioSource
3 antibodies
Boster Biological Technology
1 antibody
Cell Signaling Technology, Inc
1 antibody
FabGennix
3 antibodies
Sigma-Aldrich
4 antibodies
Creative Diagnostics
1 antibody
Abbexa
3 antibodies
ProSci
1 antibody