GPRC5A

This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008]

Description

G protein-coupled receptor class C group 5 member A

Tissue specificity

Tissue enhanced (lung, urinary bladder)

Subcell location

Vesicles, Plasma membrane

Predicted location

Intracellular, Membrane

Protein family

G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

12 (12891559 - 12917937)

Ensembl ID

ENSG00000013588  (ver. 103.38)

Orthologs

Mouse Gprc5a: ENSMUSG00000046733

UniProt

Q8NFJ5

neXtProt

NX_Q8NFJ5

Human splice variants
Mouse splice variants

Protein structure