Tissue expression
Cell line expression

THPO

gene product
MGDF, MPLLG, TPO 
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]
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Antibodies

 

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Supportive data in Antibodypedia
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633 antibodies from 36 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
180 antibodies
Biorbyt
23 antibodies
Novus Biologicals
54 antibodies
R&D Systems
10 antibodies
GeneTex
13 antibodies
Acris Antibodies GmbH
14 antibodies
LifeSpan BioSciences, Inc.
118 antibodies
OriGene
13 antibodies
Boster Biological Technology
5 antibodies
Affinity Biosciences
2 antibodies
Invitrogen Antibodies
12 antibodies
NSJ Bioreagents
5 antibodies
Abnova Corporation
6 antibodies
Bioworld Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
PeproTech Inc.
14 antibodies
Abgent
6 antibodies
NovoPro Bioscience Inc.
8 antibodies
Cusabio Biotech Co., Ltd
1 antibody
Aviva Systems Biology
5 antibodies
Bioss
1 antibody
GenWay
12 antibodies
RabMAbs
1 antibody
Abbexa
6 antibodies
MyBioSource
11 antibodies
ProSci
5 antibodies
St John's Laboratory
2 antibodies
Abiocode, Inc.
1 antibody
United States Biological
40 antibodies
Creative Diagnostics
10 antibodies
Absolute Antibody
5 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Leading Biology
3 antibodies
RayBiotech, Inc.
2 antibodies
Sino Biological Inc.
9 antibodies
Creative Biolabs
29 antibodies