AKAP7

This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Apr 2011]

Description

A-kinase anchoring protein 7

Tissue specificity

Tissue enhanced (adrenal gland)

Subcell location

Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6:q23.2 (131135467 - 131283535)

Ensembl ID

ENSG00000118507  (ver. 103.38)

Orthologs

Mouse Akap7: ENSMUSG00000039166

UniProt

O43687, Q9P0M2

neXtProt

NX_O43687, NX_Q9P0M2

Human splice variants
Mouse splice variants