ADAMTS4

gene product
ADAMTS-2, ADMP-1, KIAA0688
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq, Jul 2008]
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551 antibodies from 33 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
10 antibodies
Novus Biologicals
6 antibodies
R&D Systems
3 antibodies
antibodies-online
171 antibodies
LifeSpan BioSciences, Inc.
143 antibodies
Biorbyt
25 antibodies
Boster Biological Technology
2 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
8 antibodies
OriGene
17 antibodies
Aviva Systems Biology
3 antibodies
Bioworld Technology, Inc
1 antibody
GeneTex
6 antibodies
NSJ Bioreagents
2 antibodies
NovoPro Bioscience Inc.
6 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Acris Antibodies GmbH
12 antibodies
Creative Biolabs
31 antibodies
MyBioSource
8 antibodies
Atlas Antibodies
2 antibodies
Abgent
6 antibodies
RabMAbs
1 antibody
St John's Laboratory
3 antibodies
ProSci
3 antibodies
Abbiotec
1 antibody
United States Biological
45 antibodies
Creative Diagnostics
3 antibodies
RayBiotech, Inc.
7 antibodies
Abbexa
3 antibodies
GenWay
3 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
2 antibodies