Tissue expression
Cell line expression
Protein structure

PTPN7

Protein tyrosine phosphatase non-receptor type 7
HEPTP, LC-PTP 
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
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432 antibodies from 30 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
109 antibodies
Abnova Corporation
7 antibodies
Invitrogen Antibodies
20 antibodies
OriGene
13 antibodies
Biorbyt
99 antibodies
Proteintech Group
1 antibody
Novus Biologicals
26 antibodies
NovoPro Bioscience Inc.
3 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Acris Antibodies GmbH
13 antibodies
Aviva Systems Biology
2 antibodies
FineTest Biotech
1 antibody
GeneTex
1 antibody
Santa Cruz Biotechnology
1 antibody
ProSci
2 antibodies
Atlas Antibodies
1 antibody
RabMAbs
1 antibody
St John's Laboratory
1 antibody
MyBioSource
3 antibodies
Abbexa
5 antibodies
Creative Diagnostics
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
25 antibodies
Leading Biology
2 antibodies
Creative Biolabs
4 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Abgent
1 antibody
EMD Millipore
1 antibody