C4BPB

gene product
C4BP
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
261 antibodies from 25 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
5 antibodies
antibodies-online
81 antibodies
Biorbyt
10 antibodies
Abnova Corporation
7 antibodies
LifeSpan BioSciences, Inc.
78 antibodies
GeneTex
3 antibodies
Abbexa
1 antibody
Bioworld Technology, Inc
1 antibody
St John's Laboratory
1 antibody
Invitrogen Antibodies
3 antibodies
Aviva Systems Biology
2 antibodies
OriGene
2 antibodies
ProSci
2 antibodies
Boster Biological Technology
1 antibody
Green Mountain Antibodies
1 antibody
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
Creative Biolabs
8 antibodies
Creative Diagnostics
6 antibodies
Acris Antibodies GmbH
3 antibodies
Atlas Antibodies
1 antibody
United States Biological
37 antibodies
MyBioSource
3 antibodies
Sigma-Aldrich
2 antibodies
GenWay
1 antibody