EDARADD

gene product
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Biorbyt
10 antibodies
Novus Biologicals
1 antibody
antibodies-online
6 antibodies
LifeSpan BioSciences, Inc.
1 antibody
Acris Antibodies GmbH
1 antibody
Abnova Corporation
2 antibodies
Invitrogen Antibodies
1 antibody
MyBioSource
3 antibodies
Abiocode, Inc.
1 antibody
Creative Diagnostics
4 antibodies
Sigma-Aldrich
1 antibody
GeneTex
2 antibodies