CDK19

This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Description

cyclin-dependent kinase 19

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

6:q21 (110609978 - 110815958)

Ensembl ID

ENSG00000155111  (ver. 84.38)

Orthologs

Mouse Cdk19: ENSMUSG00000038481

UniProt

Q9BWU1

neXtProt

NX_Q9BWU1

Human splice variants
Mouse splice variants