MEP1B

gene product
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011]
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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
R&D Systems
5 antibodies
LifeSpan BioSciences, Inc.
15 antibodies
antibodies-online
12 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Biorbyt
7 antibodies
MyBioSource
1 antibody
St John's Laboratory
2 antibodies
NovoPro Bioscience Inc.
1 antibody
ProSci
1 antibody
Creative Biolabs
3 antibodies
Abbexa
1 antibody
Creative Diagnostics
1 antibody
GeneTex
1 antibody
Sigma-Aldrich
1 antibody