ALDH3A2

Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

aldehyde dehydrogenase 3 family member A2

Protein family

Disease related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

17:p11.2 (19648136 - 19685760)

Ensembl ID

ENSG00000072210  (ver. 99.38)

Orthologs

Mouse Aldh3a2: ENSMUSG00000010025

UniProt

P51648

neXtProt

NX_P51648

Human splice variants
Mouse splice variants