PRDM9

gene product
KMT8B, MSBP3, PFM6, ZNF899
The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. [provided by RefSeq, Jul 2015]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
79 antibodies from 24 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
26 antibodies
OriGene
2 antibodies
LifeSpan BioSciences, Inc.
10 antibodies
Invitrogen Antibodies
5 antibodies
Novus Biologicals
3 antibodies
Biorbyt
3 antibodies
Aviva Systems Biology
2 antibodies
Antibodies.com
1 antibody
Boster Biological Technology
1 antibody
NSJ Bioreagents
1 antibody
Creative Biolabs
3 antibodies
FabGennix
3 antibodies
ProSci
3 antibodies
Abnova Corporation
2 antibodies
Atlas Antibodies
1 antibody
St John's Laboratory
3 antibodies
Acris Antibodies GmbH
1 antibody
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody
MyBioSource
2 antibodies
Creative Diagnostics
1 antibody
Everest Biotech
1 antibody
GeneTex
1 antibody
Abgent
1 antibody