DOT1L

gene product

DOT1, KIAA1814, KMT4

The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]

Ensembl	UniProt	RefSeq	Entrez
ENST00000398665 ENSP00000381657	Q8TEK3.182 Q8TEK3	NP_115871.1 NP_115871	DOT1L 84444
ENST00000446286 ENSP00000412916	H7C3N3		DOT1L 84444
ENST00000452696 ENSP00000404284	C9JH95		DOT1L 84444
ENST00000457590 ENSP00000407411	H7C2S2		DOT1L 84444
ENST00000586024 ENSP00000476469	V9GY76		DOT1L 84444

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000105336 ENSMUSP00000100973	Q6XZL8	NP_955354.1 NP_955354	Dot1l 208266
ENSMUST00000127740 ENSMUSP00000130408	E9Q6I8		Dot1l 208266
ENSMUST00000138505 ENSMUSP00000119492	F6S070		Dot1l 208266
ENSMUST00000149394 ENSMUSP00000127762	F6SJX8		Dot1l 208266
ENSMUST00000150338 ENSMUSP00000116581	F7CVL0		Dot1l 208266

More gene data

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Atlas Antibodies

HPA071217

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Polyclonal

Western blot - Supportive data in Antibodypedia

ICC

Immunocytochemistry - Supportive data in Antibodypedia

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Supportive data in Antibodypedia

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Data in Antibodypedia (inconclusive)

535 antibodies from 31 providers.

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	Antibody	Refs	Type
Novus Biologicals 54 antibodies
	NB100-40845	11	Polyclonal
	H00084444-M01	1	Monoclonal

antibodies-online 106 antibodies
	ABIN251529	5	Polyclonal
	ABIN566567	1	Monoclonal

Abnova Corporation 6 antibodies
	H00084444-M01		Monoclonal
	PAB15852	1	Polyclonal

Bethyl Laboratories 3 antibodies
	A300-953A		Polyclonal
	A300-954A		Polyclonal

LifeSpan BioSciences, Inc. 78 antibodies
	LS-B14488		Polyclonal
	LS-B12962		Monoclonal

R&D Systems 1 antibody
	MAB6546	1	Monoclonal

Invitrogen Antibodies 43 antibodies
	A300-953A		Polyclonal
	PA5-113254		Polyclonal

Cusabio Biotech Co., Ltd 5 antibodies
	CSB-PA848418LA01HU		Polyclonal
	CSB-RA238318A0HU		Recombinant

Cell Signaling Technology, Inc 2 antibodies
	77087		Monoclonal
	90878		Monoclonal

OriGene 105 antibodies
	TA802482		Monoclonal
	TA802738		Monoclonal

Atlas Antibodies 2 antibodies
	HPA071217		Polyclonal
	HPA011875		Polyclonal

Biorbyt 17 antibodies
	orb184545		Polyclonal
	orb305478		Polyclonal

Boster Biological Technology 2 antibodies
	A00840		Polyclonal
	M00840		Monoclonal

Abbkine Scientific Co.Ltd. 1 antibody
	ABP58408		Polyclonal

Affinity Biosciences 1 antibody
	DF2490		Polyclonal

NSJ Bioreagents 2 antibodies
	F53486		Polyclonal
	F53487		Polyclonal

GeneTex 1 antibody
	GTX104736		Polyclonal

Bioss 3 antibodies
	bs-16797R		Polyclonal
	bs-16797R-Biotin		Polyclonal

MilliporeSigma / Merck KGaA 4 antibodies
	WH0084444M1		Monoclonal
	HPA011875		Polyclonal

Abiocode, Inc. 1 antibody
	R2376-2		Polyclonal

Active Motif 1 antibody
	39953		Polyclonal

ProSci 1 antibody
	30-333		Polyclonal

Proteintech Group 1 antibody
	55315-1-AP		Polyclonal

Absolute Antibody 5 antibodies
	Ab01769-1.1		Monoclonal
	Ab01769-1.6		Monoclonal

Creative Biolabs 20 antibodies
	CBMAB-D1523-YC		Recombinant
	CBMAB-K0314-LY		Recombinant

Creative Diagnostics 6 antibodies
	DCABH-6817		Monoclonal
	DPAB-DC3479		Polyclonal

United States Biological 52 antibodies
	125992		Monoclonal
	037584		Polyclonal

Abbexa 7 antibodies
	abx302555		Polyclonal
	abx006032		Polyclonal

MyBioSource 3 antibodies
	MBS9200785		Polyclonal
	MBS271960		Polyclonal

RayBiotech, Inc. 1 antibody
	101-10418		Monoclonal

RabMAbs 1 antibody
	ab157199		Monoclonal

DOT1L

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