Tissue expression
Cell line expression
Protein structure
LILRB5
Leukocyte immunoglobulin like receptor B5CD85c, LIR-8, LIR8
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
4 references | Polyclonal |
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R&D Systems | ![]() |
4 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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St John's Laboratory | ![]() |
Polyclonal |
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