Tissue expression
Cell line expression
Protein structure
SGCG
Sarcoglycan gammaA4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
Top validated antibodies |
|||||
Atlas Antibodies | HPA007476 | Polyclonal |
WB
ICC
IHC
|
||
Invitrogen Antibodies | 18102-1-AP | Polyclonal |
WB
IP
IHC
OA |
||
Proteintech Group | 18102-1-AP | Polyclonal |
WB
EL
IP
IHC |
||
Novus Biologicals | NBP2-66859 | Monoclonal |
WB
IP
IHC
ChIP |
||
NovoPro Bioscience Inc. | 115163 | Polyclonal |
WB
EL
IP
IHC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider