SAV1

gene product
salvador, WW45, WWP4
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
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228 antibodies from 23 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
66 antibodies
Novus Biologicals
26 antibodies
Abnova Corporation
8 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
3 antibodies
Abgent
4 antibodies
LifeSpan BioSciences, Inc.
28 antibodies
Invitrogen Antibodies
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
OriGene
5 antibodies
Biorbyt
12 antibodies
Creative Biolabs
12 antibodies
Aviva Systems Biology
3 antibodies
Creative Diagnostics
4 antibodies
United States Biological
38 antibodies
GeneTex
2 antibodies
St John's Laboratory
2 antibodies
Abiocode, Inc.
1 antibody
MyBioSource
2 antibodies
Sigma-Aldrich
2 antibodies
ProSci
2 antibodies
Abbexa
1 antibody
Everest Biotech
1 antibody