TMPRSS3

gene product
DFNB10, DFNB8
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
230 antibodies from 29 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
antibodies-online
73 antibodies
LifeSpan BioSciences, Inc.
37 antibodies
NovoPro Bioscience Inc.
4 antibodies
Affinity Biosciences
1 antibody
Novus Biologicals
2 antibodies
Acris Antibodies GmbH
6 antibodies
Bioworld Technology, Inc
1 antibody
Biorbyt
11 antibodies
Aviva Systems Biology
6 antibodies
OriGene
10 antibodies
Abnova Corporation
4 antibodies
GeneTex
2 antibodies
Abgent
4 antibodies
Invitrogen Antibodies
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Proteintech Group
1 antibody
RabMAbs
2 antibodies
ProSci
2 antibodies
Creative Diagnostics
4 antibodies
Creative Biolabs
2 antibodies
Arigo
1 antibody
United States Biological
37 antibodies
MyBioSource
4 antibodies
St John's Laboratory
2 antibodies
Enzo Life Sciences
2 antibodies
Sigma-Aldrich
3 antibodies