ITM2B

gene product
BRI, BRI2, BRICD2B, E25B, E3-16
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
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238 antibodies from 26 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
34 antibodies
Atlas Antibodies
2 antibodies
antibodies-online
55 antibodies
OriGene
3 antibodies
LifeSpan BioSciences, Inc.
46 antibodies
GeneTex
3 antibodies
Invitrogen Antibodies
5 antibodies
NovoPro Bioscience Inc.
2 antibodies
NSJ Bioreagents
1 antibody
Abnova Corporation
7 antibodies
Aviva Systems Biology
2 antibodies
Biorbyt
14 antibodies
St John's Laboratory
2 antibodies
Antibodies.com
1 antibody
Acris Antibodies GmbH
3 antibodies
Everest Biotech
1 antibody
ProSci
3 antibodies
Abgent
2 antibodies
Arigo
1 antibody
R&D Systems
1 antibody
Creative Biolabs
9 antibodies
MyBioSource
5 antibodies
Creative Diagnostics
4 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
27 antibodies
Sigma-Aldrich
4 antibodies