PFKP

This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Description

phosphofructokinase, platelet

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

10:p15.2 (3066333 - 3137718)

Ensembl ID

ENSG00000067057  (ver. 98.38)

Orthologs

Mouse Pfkp: ENSMUSG00000021196

UniProt

Q01813

neXtProt

NX_Q01813

Human splice variants
Mouse splice variants