Tissue expression
Cell line expression
Protein structure
SETDB2
SET domain bifurcated histone lysine methyltransferase 2C13orf4, CLLD8, CLLL8, KMT1F
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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