PTGIS

gene product
CYP8A1, PGIS
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
154 antibodies from 29 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
41 antibodies
Aviva Systems Biology
4 antibodies
Biorbyt
8 antibodies
LifeSpan BioSciences, Inc.
20 antibodies
Abnova Corporation
6 antibodies
Acris Antibodies GmbH
6 antibodies
Novus Biologicals
8 antibodies
OriGene
6 antibodies
GeneTex
3 antibodies
Abgent
3 antibodies
Atlas Antibodies
1 antibody
Santa Cruz Biotechnology
1 antibody
Invitrogen Antibodies
3 antibodies
NovoPro Bioscience Inc.
2 antibodies
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
RabMAbs
2 antibodies
ProSci
2 antibodies
R&D Systems
2 antibodies
Creative Biolabs
3 antibodies
MyBioSource
3 antibodies
RayBiotech, Inc.
3 antibodies
Creative Diagnostics
3 antibodies
St John's Laboratory
2 antibodies
Boster Biological Technology
1 antibody
United States Biological
4 antibodies
Sigma-Aldrich
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody