Tissue expression
Cell line expression
Protein structure

PRKCH

Protein kinase C eta
PKC-L, PKCL, PRKCL 
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction. [provided by RefSeq, Sep 2015]
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288 antibodies from 32 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
62 antibodies
Abnova Corporation
7 antibodies
Boster Biological Technology
3 antibodies
Invitrogen Antibodies
29 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
Atlas Antibodies
2 antibodies
OriGene
4 antibodies
Aviva Systems Biology
3 antibodies
Acris Antibodies GmbH
3 antibodies
Abgent
1 antibody
NSJ Bioreagents
1 antibody
Novus Biologicals
5 antibodies
GeneTex
3 antibodies
ProSci
2 antibodies
Bethyl Laboratories
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
RabMAbs
1 antibody
MyBioSource
6 antibodies
St John's Laboratory
23 antibodies
FabGennix
15 antibodies
Abbiotec
1 antibody
United States Biological
25 antibodies
Creative Diagnostics
3 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Leading Biology
1 antibody
EMD Millipore
2 antibodies
Abbexa
6 antibodies
Creative Biolabs
2 antibodies