Tissue expressionAmygdalaBasal gangliaCerebellumCerebral cortexChoroid plexusHippocampal formationHypothalamusMedulla oblongataMidbrainOlfactory bulbPonsSpinal cordThalamusWhite matterRetinaAdrenal glandParathyroid glandPituitary glandThyroid glandLungEsophagusSalivary glandTongueColonDuodenumRectumSmall intestineStomachGallbladderLiverPancreasKidneyUrinary bladderEpididymisProstateSeminal vesicleTestisBreastCervixEndometriumFallopian tubeOvaryPlacentaVaginaHeart muscleSkeletal muscleSmooth muscleAdipose tissueSkinAppendixBone marrowLymph nodeSpleenThymusTonsil050100150200250300350
Cell line expressionAF22GAMGSH-SY5YU-138 MGU-251 MGU-87 MGHTCEpiHTERT-RPE1OE19CACO-2Hep G2CAPAN-2HEK 293NTERA-2RPTEC TERT1RT4PC-3SuSaA-431HaCaTSK-MEL-30WM-115A549HBEC3-KTSCLC-21HAN3-CABEWOEFO-21HeLaHTERT-HME1MCF7SiHaSK-BR-3T-47dHUVEC TERT2TIMEHSkMCASC diffASC TERT1BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VFHDF/TERT166HBF TERT88HHSteCLHCN-M2RH-30U-2 OSU-2197DaudiHDLM-2HTEC/SVTERT24-BJURKATKarpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698HAP1HELHL-60HMC-1K-562NB-4THP-1U-937020406080100120140
Protein structure

ABAT

4-aminobutyrate aminotransferase
GABA-T, GABAT 
4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

Filters

Application

    Validation method

      Reference

        Provider

          Host

            Reactivity

              Antibody type

                Conjugate

                  Antigen sequence

                    Epitope

                      Antibody

                          or   Clear
                        Enhanced validation
                        Supportive data in Antibodypedia
                        Data presented on provider website
                        Data in Antibodypedia (inconclusive)
                        Recommended by provider
                        434 antibodies from 32 providers.

                        Antibody properties

                        Applications

                        or Cancel
                        Antibody
                        Refs
                        Type
                        WB
                        EL
                        ICC
                        IP
                        IHC
                        FC
                        Proteintech Group
                        1 antibody
                        Invitrogen Antibodies
                        56 antibodies
                        OriGene
                        42 antibodies
                        Antibodies.com
                        10 antibodies
                        antibodies-online
                        85 antibodies
                        Biorbyt
                        36 antibodies
                        GeneTex
                        7 antibodies
                        FineTest Biotech
                        1 antibody
                        NovoPro Bioscience Inc.
                        1 antibody
                        Novus Biologicals
                        29 antibodies
                        Atlas Antibodies
                        2 antibodies
                        Bioworld Technology, Inc
                        1 antibody
                        NSJ Bioreagents
                        1 antibody
                        Abbexa
                        8 antibodies
                        Cusabio Biotech Co., Ltd
                        3 antibodies
                        St John's Laboratory
                        2 antibodies
                        Boster Biological Technology
                        2 antibodies
                        Affinity Biosciences
                        1 antibody
                        HUABIO Research
                        1 antibody
                        Abnova Corporation
                        3 antibodies
                        Aviva Systems Biology
                        2 antibodies
                        RabMAbs
                        4 antibodies
                        Creative Biolabs
                        11 antibodies
                        Acris Antibodies GmbH
                        1 antibody
                        United States Biological
                        24 antibodies
                        MyBioSource
                        1 antibody
                        ProSci
                        1 antibody
                        MilliporeSigma / Merck KGaA
                        5 antibodies
                        Creative Diagnostics
                        3 antibodies
                        MedChemExpress LLC
                        1 antibody