Tissue expression
Cell line expression
Protein structure
ATP1B1
ATPase Na+/K+ transporting subunit beta 1ATP1B
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
Top validated antibodies |
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Proteintech Group | ![]() |
10 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
55 references | Monoclonal |
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GeneTex | ![]() |
2 references | Monoclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
13 references | Monoclonal |
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