Tissue expression
Cell line expression
Protein structure
DCLRE1C
DNA cross-link repair 1CA-SCID, ARTEMIS, FLJ11360, SCIDA, SNM1C
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
3 references | Polyclonal |
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GeneTex | ![]() |
3 references | Polyclonal |
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Abnova Corporation | ![]() |
3 references | Polyclonal |
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Acris Antibodies GmbH | ![]() |
Polyclonal |
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