Tissue expression
Cell line expression
SGCB
gene productA3b, LGMD2E, SGC
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy. [provided by RefSeq, Oct 2008]