Tissue expression
Cell line expression
Protein structure
CCL27
C-C motif chemokine ligand 27ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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R&D Systems | ![]() |
5 references | Monoclonal |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Acris Antibodies GmbH | ![]() |
Polyclonal |
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