SPAG6

gene product
CT141, pf16, Repro-SA-1
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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142 antibodies from 20 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
2 antibodies
antibodies-online
50 antibodies
Novus Biologicals
6 antibodies
GeneTex
2 antibodies
Invitrogen Antibodies
4 antibodies
LifeSpan BioSciences, Inc.
17 antibodies
Biorbyt
7 antibodies
Abnova Corporation
5 antibodies
OriGene
4 antibodies
Aviva Systems Biology
2 antibodies
Abgent
2 antibodies
Creative Biolabs
6 antibodies
Boster Biological Technology
1 antibody
St John's Laboratory
1 antibody
MyBioSource
5 antibodies
United States Biological
13 antibodies
Sigma-Aldrich
1 antibody