SLC46A1

gene product
HCP1, MGC9564, PCFT
This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
109 antibodies from 23 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
2 antibodies
OriGene
4 antibodies
LifeSpan BioSciences, Inc.
11 antibodies
Biorbyt
10 antibodies
antibodies-online
32 antibodies
Antibodies.com
1 antibody
Bethyl Laboratories
1 antibody
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
Acris Antibodies GmbH
2 antibodies
Creative Diagnostics
3 antibodies
Abnova Corporation
2 antibodies
Abgent
1 antibody
Aviva Systems Biology
1 antibody
GeneTex
1 antibody
ProSci
1 antibody
St John's Laboratory
1 antibody
MyBioSource
2 antibodies
United States Biological
12 antibodies
Invitrogen Antibodies
1 antibody
Leading Biology
1 antibody
RayBiotech, Inc.
1 antibody