Tissue expression
Cell line expression
Protein structure
RSPO2
R-spondin 2MGC35555
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Top validated antibodies |
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| Proteintech Group | 10 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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| Abcepta | Polyclonal |
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| NSJ Bioreagents | Polyclonal |
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