Tissue expression
Cell line expression
Protein structure
TDO2
Tryptophan 2,3-dioxygenaseTDO, TPH2
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
Top validated antibodies |
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| Proteintech Group | 33 references | Polyclonal |
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| Novus Biologicals | 4 references | Polyclonal |
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| LSBio | Monoclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Biorbyt | Polyclonal |
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