Tissue expression
Cell line expression
Protein structure
IARS1
Isoleucyl-tRNA synthetase 1IARS, ILRS
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
Top validated antibodies |
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| Proteintech Group | 5 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| NSJ Bioreagents | Polyclonal |
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| GeneTex | Polyclonal |
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| LSBio | Monoclonal |
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