Tissue expression
Cell line expression
Protein structure
FBXO6
F-box protein 6FBG2, FBS2, FBX6, Fbx6b
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 1 references | Polyclonal |
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| antibodies-online | 5 references | Monoclonal |
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| Invitrogen Antibodies | Monoclonal |
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| Novus Biologicals | Monoclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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