HERPUD1

gene product
HERP, KIAA0025, Mif1, SUP
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
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196 antibodies from 28 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
9 antibodies
Abnova Corporation
9 antibodies
antibodies-online
54 antibodies
NovoPro Bioscience Inc.
3 antibodies
OriGene
3 antibodies
Abgent
2 antibodies
LifeSpan BioSciences, Inc.
35 antibodies
Invitrogen Antibodies
4 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
2 antibodies
GeneTex
1 antibody
St John's Laboratory
2 antibodies
Affinity Biosciences
1 antibody
Bioworld Technology, Inc
1 antibody
Creative Biolabs
5 antibodies
Biorbyt
6 antibodies
Creative Diagnostics
5 antibodies
Aviva Systems Biology
1 antibody
MyBioSource
3 antibodies
United States Biological
26 antibodies
Abiocode, Inc.
1 antibody
Acris Antibodies GmbH
1 antibody
Cell Signaling Technology, Inc
1 antibody
RabMAbs
1 antibody
Enzo Life Sciences
2 antibodies
Sigma-Aldrich
4 antibodies
ProSci
1 antibody