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Protein structure
FBXW11
F-box and WD repeat domain containing 11BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  13149-1-AP |
15 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN952276 |
3 references | Polyclonal |
WB
EL
IHC
FC
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| Invitrogen Antibodies | 13149-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| LSBio | LS-C482886 |
Polyclonal |
WB
ICC
IHC
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| NovoPro Bioscience Inc. | 110561 |
Polyclonal |
WB
EL
IP
IHC
|
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