UBR7

This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]

Description

ubiquitin protein ligase E3 component n-recognin 7 (putative)

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

14:q32.12 (93207241 - 93229215)

Ensembl ID

ENSG00000012963  (ver. 99.38)

Orthologs

-

UniProt

Q8N806

neXtProt

NX_Q8N806

Human splice variants