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PIEZO2
Piezo type mechanosensitive ion channel component 2C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Top validated antibodies |
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| Novus Biologicals |  NBP1-78624 |
8 references | Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C180179 |
Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 26205-1-AP |
5 references | Polyclonal |
EL
IHC
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| antibodies-online | ABIN952226 |
2 references | Polyclonal |
WB
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| Atlas Antibodies | HPA040616 |
5 references | Polyclonal |
IHC
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