RASSF3

The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain. [supplied by OMIM, Jul 2003]

Description

Ras association domain family member 3

Tissue specificity

Low tissue specificity

Subcell location

Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

12 (64507001 - 64697564)

Ensembl ID

ENSG00000153179  (ver. 103.38)

Orthologs

Mouse Rassf3: ENSMUSG00000025795

UniProt

Q86WH2

neXtProt

NX_Q86WH2

Human splice variants
Mouse splice variants

Protein structure