NDRG4

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jun 2011]

Description

NDRG family member 4

Tissue specificity

Tissue enhanced (brain, heart muscle)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16:q21 (58462846 - 58513628)

Ensembl ID

ENSG00000103034  (ver. 103.38)

Orthologs

Mouse Ndrg4: ENSMUSG00000036564

UniProt

Q9ULP0

neXtProt

NX_Q9ULP0

Human splice variants
Mouse splice variants